Have you seen protondb? A pretty impressive number of games just work. Really we are at the point now where games that don’t run are more the exception, and usually it is due to Anti-cheat incompatibility or some very specific issue.

Since you mentioned darktable I assume you already know this, but depending on the camera’s raws and the presets that imagemagick has for converting these photos the results might be undesirable if not inspected or tweaked. Not disparaging any advice given here, just mentioning that generally raws are edited on a case by case basis to fix camera artifacts and color issues. Hope the solutions others have posted work out for you!