Does Godzilla have any kryptonite? If yes, he might win. If not, he loses.

Depending on which version of Superman the answer could be all over the place, but generally Superman wins unless there’s kryptonite or red sun radiation involved.

Recent versions of Superman are basically overpowered twinks. So much so that the comics have to really grasp to make him vulnerable and are really inconsistent with his power levels (which to be fair, have always been wildly inconsistent) to get him to lose or even draw a fight.

Nothing outside of reality warping godlike beings or top tier magicians have a chance of facing him, as he can just destroy most purely physical threats with a combination of strength, speed, senses, durability, and regeneration. Plus psychic resistance on top of that.

The only reason he loses as much as he does is because bad writing / “so the plot can happen”.